• In this issue of Veterinary Clinics of North America: Food Animal Practice, guest editor Dr. Robert J. Van Saun brings his considerable expertise to the topic of Ruminant Metabolic Diseases. Top experts provide a comprehensive overview of metabolic diseases and treatments in small and large ruminants caused by deficiencies of certain essential nutrients, resulting in disturbances of an animal's normal metabolic state.


    Key Features

    • Contains 12 practice-oriented topics including inflammation, immunity and transition metabolism; ketosis diagnostics and therapy; beef cattle metabolic diseases; hepatic lipidosis in ruminants; and more.

    • Provides in-depth clinical reviews on ruminant metabolic diseases, offering actionable insights for clinical practice.

    • Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

    • Cover image

    • Title page

    • Table of Contents

    • Copyright

    • Contributors

    • Forthcoming Issues

    • Preface

    • Ruminant Metabolic Diseases: Perturbed Homeorhesis

    • Key points

    • Background

    • Defining the transition period

    • Perspectives on metabolic disease

    • Lynchpins to ruminant metabolic disease

    • Perturbed homeorhesis: a new perspective

    • Clinical case outcomes

    • Clinics care points

    • Disclosures

    • Metabolic Factors at the Crossroads of Periparturient Immunity and Inflammation

    • Key points

    • Introduction

    • Periparturient innate and adaptive immunity

    • Periparturient inflammation (friend and foe)

    • Periparturient dysregulation of immunity and inflammation

    • Summary

    • Clinics care points

    • Disclosure

    • Methods of Evaluating the Potential Success or Failure of Transition Dairy Cows

    • Key points

    • Introduction to metabolic profiling in transition dairy cows

    • Blood sampling timing strategies

    • Reference interval calculation for plasma analytes in transition cows: an open issue

    • Blood sampling procedures

    • Assessing transition cows’ metabolic status through plasma analyte trends

    • Summary

    • Clinics care points

    • Disclosure

    • Considerations in the Diagnosis and Treatment of Early Lactation Calcium Disturbances

    • Key points

    • Background

    • Clinical relevance–hypocalcemia and dyscalcemia

    • Diagnosis–how and when to test

    • Therapeutic options

    • Summary

    • Clinics care points

    • Disclosure

    • Phosphorus Metabolism During Transition

    • Key points

    • Introduction

    • Background

    • Regulation of phosphorus homeostasis in cattle

    • Phosphorus balance disturbances in transition cows

    • Phosphorus requirements of dairy cows in transition

    • Future directions for research

    • Clinics care points

    • Declaration of Interests

    • Pregnancy Toxemia in Sheep and Goats

    • Key points

    • Introduction

    • Defining pregnancy toxemia

    • Etiology

    • Clinics care points

    • Disclosure

    • Supplementary data

    • Pregnancy Toxemia Therapeutic Options

    • Key points

    • Case definition

    • Intravenous dextrose

    • Clinics care points

    • Disclosure

    • Hyperketonemia: A Marker of Disease, a Sign of a High-Producing Dairy Cow, or Both?

    • Key points

    • Background

    • Physiology—the source and use of ketones in transition cows

    • Controversies—the role of hyperketonemia in health and productivity of dairy cows

    • Epidemiology—prevalence and incidence

    • Diagnosis—how to test, when to test, and how many cows?

    • Therapeutic options

    • Summary

    • Clinics care points

    • Disclosure

    • Transition Management in Grazing Systems: Pragmatism Before Precision

    • Key points

    • Background

    • System definition

    • Intensive grazing system

    • Problem definition

    • Body condition score

    • Managing pre-calving dry matter intake

    • Fortifying the transition cow diet

    • Clinics care points

    • Summary

    • Metabolic Diseases in Beef Cattle

    • Key points

    • Introduction

    • Hypomagnesemia

    • Rumen acidosis

    • Protein-energy malnutrition

    • Clinics care points

    • Disclosure

    • Urinary Calculi of Small Ruminants

    • Key points

    • Introduction

    • Clinics care points

    • Disclosure

    • Hepatic Lipidosis in Ruminants

    • Key points

    • Introduction

    • Incidence and clinical relevance

    • Cause of hepatic lipidosis

    • Hepatic lipidosis as disease component

    • Prevention of hepatic lipidosis

    • Conclusions

    • Summary

    • Clinics care points

    • Disclosure

  • Robert J. Van Saun

    Affiliations and expertise

    Department of Veterinary & Biomedical Sciences, College of Agricultural Sciences, Pennsylvania State University

Veterinary Clinics of North America
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